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Literature summary for 3.1.4.50 extracted from

  • Jian-Hua, T.; Wang-Jiao, H.; He, H.; Chao-Chao, T.; Qiong, D.; Kai-Jia, W.; Xian-Yu, Y.; Xu-Jin, Z.
    Important roles of glycosylphosphatidylinositol (GPI)-specific phospholipase D and some GPI-anchored proteins in the pathogenesis of hepatocellular carcinoma (2009), Clin. Biochem., 42, 400-407.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Hep-G2 cells Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hepatocarcinoma cell the serum GPI-PLD activities, the GPI-PLD protein expression levels, and the protein and mRNA levels of GPI-PLD in hepatocellular carcinoma are decreased by 40%, 60%, and 56%, respectively Homo sapiens
-
hepatoma cell
-
Homo sapiens
-
liver
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-O-alpha-D-galactosaminyl-2-phosphatidyl-L-chiro-inositol + H2O
-
Homo sapiens ?
-
?
glycosylphosphatidylinositol-anchored placental alkaline phosphatase + H2O
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
glycosylphosphatidylinositol-specific phospholipase D
-
Homo sapiens
GPI-PLD
-
Homo sapiens
GPI-specific phospholipase D
-
Homo sapiens