Literature summary for 3.1.4.50 extracted from

Jian-Hua, T.; Xiao-Jie, Z.; Yi-Dan, W.; Wen-Kai, L.; Wang-Jiao, H.; Cheng-Hong, W.; Gui-Yuan, L.
Effect of glycosylphosphatidylinositol specific phospholipase D gene expression levels on complement mediated killing of leukemic cells in patients with chronic myeloid leukemia (2005), Clin. Chim. Acta, 359, 115-124.

Search for more literature for 3.1.4.50

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	GPI-PDL activities and their mRNA copies in patients with chronic myeloid leukemia are significantly lower than those in healthy adults. The decreased GPI-PLD expression may reduce the release of GPI-anchored CD55 and CD59 in leukemia cells and finally decrease complement mediated killing of these cells in chronic phase of chronic myeloid leukemia	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	healthy adults and patients with chronic myeloid leukemia	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
mononuclear cell	GPI-PDL activities and their mRNA copies in patients with chronic myeloid leukemia are significantly lower than those in healthy adults	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	GPI-PDL activities and their mRNA copies in patients with chronic myeloid leukemia are significantly lower than those in healthy adults. The decreased GPI-PLD expression may reduce the release of GPI-anchored CD55 and CD59 in leukemia cells and finally decrease complement mediated killing of these cells in chronic phase of chronic myeloid leukemia	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
GPI-PDL	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)