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Literature summary for 3.1.4.50 extracted from
- Glycosylphosphatidylinositol-phospholipase D: a tool for glycosylphosphatidylinositol structural analysis (1995), Methods Enzymol., 250, 630-640.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Nonidet P-40 | stimulation | Homo sapiens |  |
| Nonidet P-40 | stimulation | Bos taurus | |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| overview | Homo sapiens |
| overview | Bos taurus |
General Stability
| General Stability | Organism |
|---|---|
| stable over a range of 0.01-0.1% detergent, ionic detergents such as SDS are inhibitory, and bicarbonate buffer is inhibitory | Homo sapiens |
| stable over a range of 0.01-0.1% detergent, ionic detergents such as SDS are inhibitory, and bicarbonate buffer is inhibitory | Bos taurus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,10-phenanthroline | - |
Bos taurus | |
| 1,10-phenanthroline | - |
Homo sapiens | |
| Bicarbonate buffer | - |
Bos taurus | |
| Bicarbonate buffer | - |
Homo sapiens | |
| EGTA | - |
Bos taurus | |
| EGTA | - |
Homo sapiens | |
| lipid A | - |
Bos taurus | |
| lipid A | - |
Homo sapiens | |
| lysophosphatidic acid | - |
Bos taurus | |
| lysophosphatidic acid | - |
Homo sapiens | |
| phosphatidic acid | - |
Bos taurus | |
| phosphatidic acid | - |
Homo sapiens | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | activation | Homo sapiens | |
| Ca2+ | activation | Bos taurus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 100000 | - |
gel filtration | Bos taurus |
| 110000 | - |
gel filtration | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| plasma | - |
Homo sapiens | - |
| plasma | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | no substrate: phosphatidylethanolamine, phosphatidylcholine, phosphatidylinositol derived from HNO2-cleaved mfVSG, overview on substrate specificity | Homo sapiens | ? | - |
? | |
| additional information | no substrate: phosphatidylethanolamine, phosphatidylcholine, phosphatidylinositol derived from HNO2-cleaved mfVSG, overview on substrate specificity | Bos taurus | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 110000 | Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
assay at | Homo sapiens |
| 7.4 | - |
assay at | Bos taurus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 5 | 8 | - |
Homo sapiens |
| 5 | 8 | - |
Bos taurus |
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Release 2023.1 (January 2023)
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