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Literature summary for 3.1.4.46 extracted from
- Mammalian glycerophosphodiester phosphodiesterases (2007), Biosci. Biotechnol. Biochem., 71, 1811-1818.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Escherichia coli | 5829 | - |
| outer membrane | - |
Haemophilus influenzae | 19867 | - |
| periplasm | - |
Escherichia coli | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glycerophosphocholine + H2O | Escherichia coli | reaction provides choline which is an essential growth factor in bacteria | sn-glycerol 3-phosphate + choline | - |
? |  |
| glycerophosphocholine + H2O | Haemophilus influenzae | utilization of glycerophosphocholine and incorporation of choline from host cell membranes | sn-glycerol 3-phosphate + choline | - |
? | |
| glycerophosphodiester + H2O | Escherichia coli | important for sn-glycerol-3-phosphate uptake, which serves as carbon and phosphate source | sn-glycerol 3-phosphate + alcohol | - |
? | |
| glycerophosphoethanolamine + H2O | Escherichia coli | reaction provides ethanolamine which is an essential growth factor in bacteria | sn-glycerol 3-phosphate + ethanolamine | - |
? | |
| additional information | Haemophilus influenzae | enzyme responsible for interaction with immunoglobulin D, important virulence factor | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | P09394 | - |
- |
| Escherichia coli | P10908 | - |
- |
| Haemophilus influenzae | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glycerophosphocholine + H2O | reaction provides choline which is an essential growth factor in bacteria | Escherichia coli | sn-glycerol 3-phosphate + choline | - |
? | |
| glycerophosphocholine + H2O | utilization of glycerophosphocholine and incorporation of choline from host cell membranes | Haemophilus influenzae | sn-glycerol 3-phosphate + choline | - |
? | |
| glycerophosphodiester + H2O | important for sn-glycerol-3-phosphate uptake, which serves as carbon and phosphate source | Escherichia coli | sn-glycerol 3-phosphate + alcohol | - |
? | |
| glycerophosphoethanolamine + H2O | reaction provides ethanolamine which is an essential growth factor in bacteria | Escherichia coli | sn-glycerol 3-phosphate + ethanolamine | - |
? | |
| additional information | enzyme responsible for interaction with immunoglobulin D, important virulence factor | Haemophilus influenzae | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GlpQ | - |
Haemophilus influenzae |
| GlpQ | - |
Escherichia coli |
| GP-PDE | - |
Haemophilus influenzae |
| GP-PDE | - |
Escherichia coli |
| UgpQ | - |
Escherichia coli |
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Release 2023.1 (January 2023)
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