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Literature summary for 3.1.4.41 extracted from

  • Kurpiewski, G.; Forrester, L.J.; Barrett, J.T.; Campbell, B.J.
    Platelet aggregation and sphingomyelinase D activity of a purified toxin from the venom of Loxosceles rescula (1981), Biochim. Biophys. Acta, 678, 467-476.
    View publication on PubMed
Search for more literature for 3.1.4.41

Inhibitors

Inhibitors Comment Organism Structure
additional information enzyme induced human platelet aggregation is inhibited by EDTA over a range of 0.6 to 3.0 mM Loxosceles reclusa

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
32000
-
 4 * 32000, SDS-PAGE Loxosceles reclusa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Loxosceles reclusa enzyme is a poisonous toxin which induces platelet aggregation ?
-
 ?

Organism

Organism UniProt Comment Textmining
Loxosceles reclusa
-
 brown recluse spider
-

Purification (Commentary)

Purification (Comment) Organism
partial Loxosceles reclusa

Source Tissue

Source Tissue Comment Organism Textmining
venom gland
-
 Loxosceles reclusa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Loxosceles reclusa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-alpha-[palmitoyl-1]lysophosphatidylcholine + H2O
-
 Loxosceles reclusa ?
-
 ?
additional information enzyme is a poisonous toxin which induces platelet aggregation Loxosceles reclusa ?
-
 ?
sphingomyelin + H2O
-
 Loxosceles reclusa N-acylsphingosylphosphate + choline
-
 ?

Subunits

Subunits Comment Organism
tetramer 4 * 32000, SDS-PAGE Loxosceles reclusa