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Literature summary for 3.1.4.4 extracted from
- Dual functions of phospholipase Dalpha1 in plant response to drought (2008), Mol. Plant, 1, 262-269.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| functional overexpression of isozyme PLDalpha1 in Nicotiana tabacum transgenic plants under the control of the 35S promoter | Arabidopsis thaliana |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | Nicotiana tabacum transgenic plants, overexpressing Arabidopsis thaliana isozyme PLDalpha1, display more susceptibility to drought than control plants, drought also induces an increase in PLDa1 activity. High level of PLDalpha1 activity is correlated to membrane degradation in late stages of drought, as demonstrated by ionic leakage and lipid peroxidation. Recombinant PLD2 promotes stomatal closure at earlier stages, but disrupts membranes in prolonged drought stress, phenotype, overview | Arabidopsis thaliana |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Arabidopsis thaliana | 16020 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Arabidopsis thaliana | PLDalpha1 interacts with the Galpha1 subunit of the heterotrimeric G protein to inhibit stomatal opening | ? | - |
? |  |
| phosphatidylcholine + H2O | Arabidopsis thaliana | - |
choline + phosphatidic acid | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arabidopsis thaliana | - |
isozyme PLDalpha1 | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| guard cell | isozyme PLDalpha1 is presented in guard cells in a much higher level than other PLDs in Arabidopsis thaliana | Arabidopsis thaliana | - |
| leaf | - |
Arabidopsis thaliana | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | PLDalpha1 interacts with the Galpha1 subunit of the heterotrimeric G protein to inhibit stomatal opening | Arabidopsis thaliana | ? | - |
? | |
| phosphatidylcholine + H2O | - |
Arabidopsis thaliana | choline + phosphatidic acid | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| phospholipase Dalpha1 | - |
Arabidopsis thaliana |
| PLDalpha1 | - |
Arabidopsis thaliana |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | role of PLDalpha1 in promoting abscisic acid sensitivity and stomatal closure. PLDalpha1 and phosphatidic acid regulate stomatal closure via a bifurcating pathway and interacts with the Galpha1 subunit of the heterotrimeric G protein to inhibit stomatal opening. PLDalpha1-derived phosphatidic acid binds to ABI1, a protein phosphatase 2C, that functions as a negative regulator in the abscisic acid signaling pathway, overview | Arabidopsis thaliana |
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