Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.4.4 extracted from

  • Brandenburg, L.O.; Seyferth, S.; Wruck, C.J.; Koch, T.; Rosenstiel, P.; Lucius, R.; Pufe, T.
    Involvement of phospholipase D 1 and 2 in the subcellular localization and activity of formyl-peptide-receptors in the human colonic cell line HT29 (2009), Mol. Membr. Biol., 26, 371-383.
    View publication on PubMed
Search for more literature for 3.1.4.4

Protein Variants

Protein Variants Comment Organism
additional information PLD1 silencing by siRNA in HT-29 cells affects formyl peptide receptor, FPRL1 and FPRL2, activity, overview Homo sapiens
additional information PLD2 silencing by siRNA in HT-29 cells affects formyl peptide receptor, FPRL1 and FPRL2, activity, overview Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens O14939 PLD2; isozyme PLD2
-
Homo sapiens Q13393 PLD1; isozyme PLD1
-

Source Tissue

Source Tissue Comment Organism Textmining
HT-29 cell a colonic cell line, expression of isozymes PLD1 and PLD2, overview Homo sapiens
-

Synonyms

Synonyms Comment Organism
phospholipase D1
-
 Homo sapiens
phospholipase D2
-
 Homo sapiens
PLD1
-
 Homo sapiens
PLD2
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function PLD is a key enzyme involved in secretion, endocytosis and receptor signalling with importance of PLD1 in formyl peptide receptor, FPRL1 and FPRL2, function. Function in endocytosis, receptor recycling, and reactivation for receptor activity, overview Homo sapiens
physiological function PLD is a key enzyme involved in secretion, endocytosis and receptor signalling with importance of PLD2 in formyl peptide receptor, FPRL1 and FPRL2, function. Function in endocytosis, receptor recycling, and reactivation for receptor activity, overview Homo sapiens