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Literature summary for 3.1.4.4 extracted from
- Parathyroid hormone stimulates phosphatidylethanolamine hydrolysis by phospholipase D in osteoblastic cells (2005), Lipids, 40, 1135-1140.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| phosphatidylcholine + H2O | Rattus norvegicus | both phosphatidylcholine and phosphatidylethanolamine are substrates for phospholipase D in UMR-106 osteoblastic cells and can therefore be sources of phospholipid hydrolysis products for downstream signaling in osteoblast | 1,2-diacylglycerophosphate + choline | - |
? |  |
| phosphatidylethanolamine + H2O | Rattus norvegicus | parathyroid hormone stimulates phosphatidylethanolamine hydrolysis by phospholipase D in osteoblastic cells. Both phosphatidylcholine and phosphatidylethanolamine are substrates for phospholipase D in UMR-106 osteoblastic cells and can therefore be sources of phospholipid hydrolysis products for downstream signaling in osteoblast | 1,2-diacylglycerophosphate + ethanolamine | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| UMR-106 cell | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| phosphatidylcholine + H2O | - |
Rattus norvegicus | 1,2-diacylglycerophosphate + choline | - |
? | |
| phosphatidylcholine + H2O | both phosphatidylcholine and phosphatidylethanolamine are substrates for phospholipase D in UMR-106 osteoblastic cells and can therefore be sources of phospholipid hydrolysis products for downstream signaling in osteoblast | Rattus norvegicus | 1,2-diacylglycerophosphate + choline | - |
? | |
| phosphatidylethanolamine + H2O | - |
Rattus norvegicus | 1,2-diacylglycerophosphate + ethanolamine | - |
? | |
| phosphatidylethanolamine + H2O | parathyroid hormone stimulates phosphatidylethanolamine hydrolysis by phospholipase D in osteoblastic cells. Both phosphatidylcholine and phosphatidylethanolamine are substrates for phospholipase D in UMR-106 osteoblastic cells and can therefore be sources of phospholipid hydrolysis products for downstream signaling in osteoblast | Rattus norvegicus | 1,2-diacylglycerophosphate + ethanolamine | - |
? | |
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