Literature summary for 3.1.4.4 extracted from

Devlin, M.A.; Das, S.; Singh, I.; Bourgoin, S.; Brindley, D.N.; Ginsberg, J.
The characterization of phospholipase D in FRTL-5 thyroid cells (2000), Mol. Cell. Endocrinol., 167, 107-115.

Search for more literature for 3.1.4.4

Activating Compound

Activating Compound	Comment	Organism	Structure
GTPgammaS	membrane fraction, 5fold increase in activity, membrane plus cytosolic fraction, 8fold increase in activity	Rattus norvegicus
thyrotropin	PLD-1, stimulation up to 2.3fold, accompanied by translocation of ADP-ribosylation factor and RhoA to the membrane fraction	Rattus norvegicus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	PLD-1, about 80% of total activity, PLD-2, about 20% of total acttivity	Rattus norvegicus	16020	-

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
100000	-	x * 120000, PLD-1, x * 100000, PLD-2, SDS-PAGE	Rattus norvegicus
120000	-	x * 120000, PLD-1, x * 100000, PLD-2, SDS-PAGE	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
FRTL-5 cell	-	Rattus norvegicus	-

Subunits

Subunits	Comment	Organism
?	x * 120000, PLD-1, x * 100000, PLD-2, SDS-PAGE	Rattus norvegicus

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Release 2023.1 (January 2023)