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Literature summary for 3.1.4.39 extracted from

  • Tsuboi, K.; Okamoto, Y.; Rahman, I.A.; Uyama, T.; Inoue, T.; Tokumura, A.; Ueda, N.
    Glycerophosphodiesterase GDE4 as a novel lysophospholipase D a possible involvement in bioactive N-acylethanolamine biosynthesis (2015), Biochim. Biophys. Acta, 1851, 537-548 .
    View publication on PubMed
Search for more literature for 3.1.4.39

Cloned(Commentary)

Cloned (Comment) Organism
expression in HEK-293 cell Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane recombinant enzyme Mus musculus 16020
-

Organism

Organism UniProt Comment Textmining
Mus musculus Q9CRY7 isoform GDE4
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Mus musculus
-
colon
-
 Mus musculus
-
ileum
-
 Mus musculus
-
stomach
-
 Mus musculus
-
testis
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
lysophosphatidyl choline + H2O
-
 Mus musculus lysophosphatidic acid + choline
-
 ?
lysophosphatidyl ethanolamine + H2O
-
 Mus musculus lysophosphatidic acid + ethanolamine
-
 ?
N-palmitoyllysophosphatidylethanolamine + H2O
-
 Mus musculus lysophosphatidic acid + N-palmitoylethanolamine
-
 ?

Synonyms

Synonyms Comment Organism
GDE4
-
 Mus musculus
GDPD1
-
 Mus musculus

General Information

General Information Comment Organism
physiological function GDE4 functions as an N-acylethanolamine-generating lysophospholipase D in living cells. The expression of GDE4 increases the levels of most species of lysophosphatidic acid in the cell Mus musculus