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Literature summary for 3.1.4.39 extracted from
- Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1 (2004), J. Biol. Chem., 279, 17634-17639.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | tumor cell motility-stimulating factor, represents a potential target for cancer therapy | Mus musculus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ki16425 | inhibits the migratory response of lysophosphatidic acid1-expressing cells to both lysophosphatidic acid and ATX | Mus musculus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| skin fibroblast | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| lysophosphatidylcholine + H2O | - |
Mus musculus | lysophosphatidic acid + choline | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ATX | - |
Mus musculus |
| autotaxin | - |
Mus musculus |
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