Literature summary for 3.1.4.39 extracted from

Kehlen, A.; Englert, N.; Seifert, A.; Klonisch, T.; Dralle, H.; Langner, J.; Hoang-Vu, C.
Expression, regulation and function of autotaxin in thyroid carcinomas (2004), Int. J. Cancer, 109, 833-838.

Search for more literature for 3.1.4.39

Activating Compound

Activating Compound	Comment	Organism	Structure
bFGF	induces a 1.9fold higher ATX mRNA expression	Homo sapiens
EGF	induces a 2.3fold higher ATX mRNA expression	Homo sapiens
IL-6	induces a marked increase in ATX mRNA expression	Homo sapiens

Application

Application	Comment	Organism
medicine	tumor cell motility-stimulating factor	Homo sapiens
molecular biology	is involved in the regulation of IL-8 and CD54 gene	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
thyroid cancer cell line	-	Homo sapiens	-

Storage Stability

Storage Stability	Organism
-80°C	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
lysophosphatidylcholine + H2O	-	Homo sapiens	lysophosphatidic acid + choline	-	?

Synonyms

Synonyms	Comment	Organism
ATX/NPP2	-	Homo sapiens
autotaxin	-	Homo sapiens
lysophospholipase D	-	Homo sapiens
lysoPLD	-	Homo sapiens

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Release 2023.1 (January 2023)