Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Bos taurus | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
retina | - |
Bos taurus | - |
retinal rod | - |
Bos taurus | - |
Subunits | Comment | Organism |
---|---|---|
More | rod photoreceptor cGMP phosphodiesterase consists of a catalytic subunit complex, Palphabeta, and two inhibitory subunits, Pgamma. Isolation of Palphalphabetagammaagammadelta and Palphabetagammadeltadelta suggests that one C-terminus of Palphabeta is involved in the Palphabetagammagamma interaction with membranes, and that Pgamma dissociation opens another C-terminus for Pdelta, a prenyl-binding protein, binding, which may lead to the expression of high PDE activity. Extraction, isolation and analysis of diverse subunit complexes, detailed overview | Bos taurus |
tetramer | alphabeta(gamma)2 | Bos taurus |
Synonyms | Comment | Organism |
---|---|---|
cGMP phosphodiesterase6 | - |
Bos taurus |
PDE6 | - |
Bos taurus |
General Information | Comment | Organism |
---|---|---|
evolution | mechanisms for PDE activation are similar in mammalian and amphibian photoreceptors as well as in rods and cones | Bos taurus |
malfunction | identification of a Pgamma-depleted PDE as Palphabetagamma, detailed overview | Bos taurus |