Application | Comment | Organism |
---|---|---|
medicine | phosphodiesterase-5 inhibitors promote nitric oxide activity and enhance vasodilation. Infusion of PDE5 inhibitor sildenafil alone reduceds systemic and pulmonary artery blood pressure, while maintaining cardiac output and oxygen delivery. Combined hemoglobin-based oxygen carriers and sildenafil infusion results in stable systemic blood pressure, cardiac output, and oxygen delivery | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
sildenafil | PDE5 inhibitor | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
PDE5 | - |
Rattus norvegicus |
phosphodiesterase-5 | - |
Rattus norvegicus |