Literature summary for 3.1.4.35 extracted from

Chen, C.Y.; Chang, Y.H.; Bau, D.T.; Huang, H.J.; Tsai, F.J.; Tsai, C.H.; Chen, C.Y.
Discovery of potent inhibitors for phosphodiesterase 5 by virtual screening and pharmacophore analysis (2009), Acta Pharmacol. Sin., 30, 1186-1194.

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Inhibitors

Inhibitors	Comment	Organism	Structure
3-[(6-deoxy-alpha-L-mannopyranosyl)oxy]-5-hydroxy-8-(1-hydroxy-2-methylprop-2-en-1-yl)-2-(4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl beta-D-glucopyranoside	-	Homo sapiens
6-deoxy-3-O-[6-deoxy-4-O-[7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-8-(2-methylprop-1-en-1-yl)-4-oxo-3,4-dihydro-2H-chromen-3-yl]-alpha-L-mannopyranosyl]-alpha-L-mannopyranose	-	Homo sapiens
Evo48	potent inhibitor of PDE5	Homo sapiens
sildenafil	-	Homo sapiens
tadalafil	-	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3',5'-cGMP + H2O	Homo sapiens	-	5'-GMP	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3',5'-cGMP + H2O	-	Homo sapiens	5'-GMP	-	?

Synonyms

Synonyms	Comment	Organism
PDE5	-	Homo sapiens
phosphodiesterase 5	-	Homo sapiens

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Release 2023.1 (January 2023)