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Literature summary for 3.1.4.35 extracted from

  • Wang, S.; Ning, G.; Chen, X.; Yang, J.; Ouyang, H.; Zhang, H.; Tai, P.; Mu, X.; Zhou, B.; Zhang, M.; Xia, G.
    PDE5 modulates oocyte spontaneous maturation via cGMP-cAMP but not cGMP-PKG signaling (2008), Front. Biosci., 13, 7087-7095.
    View publication on PubMed
Search for more literature for 3.1.4.35

Inhibitors

Inhibitors Comment Organism Structure
sildenafil
-
 Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
oocyte PDE5 plays a role in regulating spontaneous maturation of oocytes Mus musculus
-
ovarian cumulus cell PDE5 is present in cumulus cells of big, antral follicles Mus musculus
-
ovary
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3',5'-cGMP + H2O PDE5 is specific for cGMP Mus musculus 5'-GMP
-
 ?

Synonyms

Synonyms Comment Organism
cGMP binding phosphodiesterase
-
 Mus musculus
PDE5
-
 Mus musculus
phosphodiesterase type 5
-
 Mus musculus