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Literature summary for 3.1.4.35 extracted from
- The effect of selective inhibition of cyclic GMP hydrolyzing phosphodiesterases 2 and 5 on learning and memory processes and nitric oxide synthase activity in brain during aging (2008), Brain Res., 1216, 68-77.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| zaprinast | - |
Rattus norvegicus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Rattus norvegicus | - |
| cerebral cortex | - |
Rattus norvegicus | - |
| hippocampus | - |
Rattus norvegicus | - |
| striatum | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3',5'-cGMP + H2O | - |
Rattus norvegicus | 5'-GMP | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| cyclic GMP hydrolyzing phosphodiesterase 5 | - |
Rattus norvegicus |
| PDE5 | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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