Literature summary for 3.1.4.35 extracted from

Werkstroem, V.; Svensson, A.; Andersson, K.E.; Hedlund, P.
Phosphodiesterase 5 in the female pig and human urethra: morphological and functional aspects (2006), BJU Int., 98, 414-423.

Search for more literature for 3.1.4.35

Inhibitors

Inhibitors	Comment	Organism	Structure
sildenafil	nerve-induced relaxation of urethral preparations are enhanced at low concentrations of sildenafil, with direct smooth muscle-relaxant actions of the inhibitors at high concentrations	Sus scrofa
tadalafil	nerve-induced relaxation of urethral preparations are enhanced at low concentrations of tadalafil, with direct smooth muscle-relaxant actions of the inhibitors at high concentrations	Sus scrofa
vardenafil	nerve-induced relaxation of urethral preparations are enhanced at low concentrations of vardenafil, with direct smooth muscle-relaxant actions of the inhibitors at high concentrations	Sus scrofa

Organism

Organism	UniProt	Comment	Textmining
Sus scrofa	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
urethra	wide distribution of enzyme isoform PDE5, nerve-induced relaxation of urethral preparations are enhanced at low concentrations of enzyme inhibitors sildenafil, vardenafil, and tadalafil, with direct smooth muscle-relaxant actions of the inhibitors at high concentrations	Sus scrofa	-

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)