Literature summary for 3.1.4.35 extracted from

Ko, W.C.; Shih, C.M.; Lai, Y.H.; Chen, J.H.; Huang, H.L.
Inhibitory effects of flavonoids on phosphodiesterase isozymes from guinea pig and their structure-activity relationships (2004), Biochem. Pharmacol., 68, 2087-2094.

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Inhibitors

Inhibitors	Comment	Organism	Structure
diosmetin	IC50: 0.015 mM, PDB5	Cavia porcellus
genistein	IC50: 0.073 mM, PDB5	Cavia porcellus
luteolin	IC50: 0.0193 mM, PDB5	Cavia porcellus

Organism

Organism	UniProt	Comment	Textmining
Cavia porcellus	-	-	-

Synonyms

Synonyms	Comment	Organism
PDB5	-	Cavia porcellus

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.015	-	IC50: 0.015 mM, PDB5	Cavia porcellus	diosmetin
0.0193	-	IC50: 0.0193 mM, PDB5	Cavia porcellus	luteolin
0.073	-	IC50: 0.073 mM, PDB5	Cavia porcellus	genistein

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Release 2023.1 (January 2023)