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Literature summary for 3.1.4.35 extracted from

  • van Staveren, W.C.; Glick, J.; Markerink-van Ittersum, M.; Shimizu, M.; Beavo, J.A.; Steinbusch, H.W.; de Vente, J.
    Cloning and localization of the cGMP-specific phosphodiesterase type 9 in the rat brain (2002), J. Neurocytol., 31, 729-741.
    View publication on PubMed
Search for more literature for 3.1.4.35

Cloned(Commentary)

Cloned (Comment) Organism
-
 Mus musculus
cloning of EST Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
61756
-
 x * 61756, deduced from nucleotide sequence Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
guanosine 3',5'-cyclic phosphate + H2O Rattus norvegicus
-
 guanosine 5'-phosphate
-
 ?
guanosine 3',5'-cyclic phosphate + H2O Mus musculus
-
 guanosine 5'-phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus O70628
-
-
Rattus norvegicus Q8QZV1
-
-

Source Tissue

Source Tissue Comment Organism Textmining
astrocyte
-
 Rattus norvegicus
-
astrocyte
-
 Mus musculus
-
brain
-
 Rattus norvegicus
-
brain
-
 Mus musculus
-
cerebellum strongest PDE9A expression in Purkinje cells Rattus norvegicus
-
cerebellum strongest PDE9A expression in Purkinje cells Mus musculus
-
hippocampus pyramidal cells and granule cells Rattus norvegicus
-
hippocampus pyramidal cells and granule cells Mus musculus
-
neuron
-
 Rattus norvegicus
-
neuron
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
guanosine 3',5'-cyclic phosphate + H2O
-
 Rattus norvegicus guanosine 5'-phosphate
-
 ?
guanosine 3',5'-cyclic phosphate + H2O
-
 Mus musculus guanosine 5'-phosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 61756, deduced from nucleotide sequence Rattus norvegicus

Synonyms

Synonyms Comment Organism
cGMP-specific phosphodiesterase type 9
-
 Rattus norvegicus
cGMP-specific phosphodiesterase type 9
-
 Mus musculus
PDE9A
-
 Rattus norvegicus
PDE9A1
-
 Mus musculus