Inhibitors | Comment | Organism | Structure |
---|---|---|---|
tricyclodecan-9-yl-xanthogenate | i.e. D609, specific inhibitor, does not inhibit sphingomyelin synthase | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphatidylcholine + H2O | Rattus norvegicus | - |
1,2-sn-diacylglycerol + phosphocholine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
bone marrow stromal cell | cholinergic neuron-like cells | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphatidylcholine + H2O | - |
Rattus norvegicus | 1,2-sn-diacylglycerol + phosphocholine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PC-PLC | - |
Rattus norvegicus |
phosphatidylcholine-specific phospholipase C | - |
Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
evolution | the enzyme is a the member of phospholipase C family | Rattus norvegicus |
physiological function | the enzyme is involved in PC-PLC-medicated neuronal differentiation of bone marrow stromal cells, and heat shock protein 70 is the pivotal factor by blocking phospholipase C inhibitor D609-induced increase of transcription factor B-cell translocation gene 2 expression and cholinergic neuronal differentiation of bone marrow stromal cells, overview | Rattus norvegicus |