Literature summary for 3.1.4.3 extracted from

Upham, B.L.; Blaha, L.; Babica, P.; Park, J.S.; Sovadinova, I.; Pudrith, C.; Rummel, A.M.; Weis, L.M.; Sai, K.; Tithof, P.K.; Guzvi?, M.; Vondracek, J.; Machala, M.; Trosko, J.E.
Tumor promoting properties of a cigarette smoke prevalent polycyclic aromatic hydrocarbon as indicated by the inhibition of gap junctional intercellular communication via phosphatidylcholine-specific phospholipase C (2008), Cancer Sci., 99, 696-705.

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Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	inhibition of phosphatidylcholine-specific phospholipase C prevents the inhibition of gap junctional intercellular communication by 1-methylanthracene	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
WB-F344 cell	rat liver epithelial cells	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
phosphatidylcholine + H2O	-	Rattus norvegicus	1,2-diacylglycerol + phosphorylcholine	-	?

Synonyms

Synonyms	Comment	Organism
phosphatidylcholine specific phospholipase C	-	Rattus norvegicus

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Release 2023.1 (January 2023)