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Literature summary for 3.1.4.3 extracted from

  • Rose, T.M.; Prestwich, G.D.
    Synthesis and evaluation of fluorogenic substrates for phospholipase D and phospholipase C (2006), Org. Lett., 8, 2575-2578.
    View publication on PubMedView publication on EuropePMC
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Application

Application Comment Organism
analysis synthesis of fluorogenic analogue of phosphatidylcholine 1-O-(6-(p-methyl red)-amino-hexanoyl)-2-O-(12-(p-methyl red)-amino-dodecanoyl)-sn-glyceryl-N-(3-(5-BODIPY-pentanoyl)-amino-propyl)-N,Ndimethyl-phosphatidylethanolamine, and use as direct substrate for real-time measurement of enzyme activity. Substrate for both phospholipases C and D and lysophospholipase D, no substrate for Bacillus cereus PI-PLC or Clostridium perfringens PC-PLC Bacillus cereus

Organism

Organism UniProt Comment Textmining
Bacillus cereus
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 isoform PC-PLC
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-O-(6-(p-methyl red)-amino-hexanoyl)-2-O-(12-(p-methyl red)-amino-dodecanoyl)-sn-glyceryl-N-(3-(5-BODIPY-pentanoyl)-amino-propyl)-N,Ndimethyl-phosphatidylethanolamine + H2O fluorogenic analogue of phosphatidylcholine, direct substrate for real-time measurement of enzyme activity Bacillus cereus ?
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 ?