Inhibitors | Comment | Organism | Structure |
---|---|---|---|
D609 | i.e. tricyclodecan-9-yl potassium xanthate, inhibition of isoform PC-PLC. After application on blastodisc at 24 h, cell differentiation cannot progress and intracellular level of reactive oxygen species is elevated | Gallus gallus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Gallus gallus | isoform PC-PLC and reactive oxygen species are involved in chicken blastodisc differentiation to vascular endothelial cells | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Gallus gallus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blastodisc | in vitro vasculogenesis model. Activities of both Ca2+-dependent and independent isoform PC-PLC and the level of reactive oxygen species are elevated during the endothelial differentiation of the blastodisc. Ca2+-independent PC-PLC undergoes an increase in 24 h, then decreases gradually with the cell differentiation, while Ca2+-dependent PC-PLC is almost not changed during the process | Gallus gallus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | isoform PC-PLC and reactive oxygen species are involved in chicken blastodisc differentiation to vascular endothelial cells | Gallus gallus | ? | - |
? |