Literature summary for 3.1.4.3 extracted from

Cheng, Y.; Zhao, Q.; Liu, X.; Araki, S.; Zhang, S.; Miao, J.
Phosphatidylcholine-specific phospholipase C, p53 and ROS in the association of apoptosis and senescence in vascular endothelial cells (2006), FEBS Lett., 580, 4911-4915.

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Inhibitors

Inhibitors	Comment	Organism	Structure
D609	suppression of isoform PC-PLC by D609 inhibits apoptosis in young cells, but not in senescent cells, and depresses reactive oxygen species levels in both young and senescent cells	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
HUVEC cell	suppression of isoform PC-PLC inhibits apoptosis in young cells, but not in senescent cells, and depresses reactive oxygen species levels in both young and senescent cells	Homo sapiens	-

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Release 2023.1 (January 2023)