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Literature summary for 3.1.4.2 extracted from

  • Spanner, S.; Ansell, G.B.
    Activation of glycerophosphocholine phosphodiesterase in rat forebrain by Ca2+ (1982), Biochem. J., 208, 845-850.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.4.2

Inhibitors

Inhibitors Comment Organism Structure
EDTA complete inhibition at 0.005 mM Rattus sp.
EGTA
-
 Rattus sp.

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane significant levels in neurons and glia Rattus sp. 5886
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ activation at very low concentration Rattus sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
sn-glycero 3-phosphorylcholine + H2O Rattus sp. cellular phosphatidylcholine catabolic pathway ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus sp.
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
forebrain
-
 Rattus sp.
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.005
-
-
 Rattus sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
sn-glycero 3-phosphorylcholine + H2O
-
 Rattus sp. sn-glycerol 3-phosphate + choline
-
 ?
sn-glycero 3-phosphorylcholine + H2O cellular phosphatidylcholine catabolic pathway Rattus sp. ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8 8.6
-
 Rattus sp.