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Literature summary for 3.1.4.17 extracted from

  • Santone, R.; Giorgi, M.; Maccarone, R.; Basso, M.; Deplano, S.; Bisti, S.
    Gene expression and protein localization of calmodulin-dependent phosphodiesterase in adult rat retina (2006), J. Neurosci. Res., 84, 1020-1026.
    View publication on PubMed
Search for more literature for 3.1.4.17

Activating Compound

Activating Compound Comment Organism Structure
Ca2+ isoform PDE1, stimulation of both hydrolysis of cAMP and cGMP Rattus norvegicus
Calmodulin isoform PDE1, stimulation of both hydrolysis of cAMP and cGMP Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
63000
-
 x * 63000, splice variant PDE1B, x * 74000 and x * 70000, splice variant PDE1C, x * 79000, splice variant PDE1A Rattus norvegicus
70000
-
 x * 63000, splice variant PDE1B, x * 74000 and x * 70000, splice variant PDE1C, x * 79000, splice variant PDE1A Rattus norvegicus
74000
-
 x * 63000, splice variant PDE1B, x * 74000 and x * 70000, splice variant PDE1C, x * 79000, splice variant PDE1A Rattus norvegicus
79000
-
 x * 63000, splice variant PDE1B, x * 74000 and x * 70000, splice variant PDE1C, x * 79000, splice variant PDE1A Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 isoform PDE1
-

Source Tissue

Source Tissue Comment Organism Textmining
retina splice variant PDE1A is distributed in outer retina, especially in the outer segments of photoreceptors. Variant PDE1B is uniformly distributed across the retina, PDE1C is confined mainly to the inner retina with precise localization to the inner nuclear layer Rattus norvegicus
-

Subunits

Subunits Comment Organism
? x * 63000, splice variant PDE1B, x * 74000 and x * 70000, splice variant PDE1C, x * 79000, splice variant PDE1A Rattus norvegicus