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Literature summary for 3.1.4.17 extracted from

  • Yu, J.; Wolda, S.L.; Frazier, A.L.B.; Florio, V.A.; Martins, T.J.; Snyder, P.B.; Harris, E.A.S.; McCaw, K.N.; Farrell, C.A.; Steiner, B.; Bentley J.K.; Beavo, J.A.; Ferguson, K.; Gelinas, R.
    Identification and characterization of a human calmodulin-stimulated phosphodiesterase PDE1B1 (1997), Cell. Signal., 9, 519-529.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
expression in Saccharomyces cerevisiae Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
3-isobutyl-1-methylxanthine
-
 Homo sapiens
8-methoxymethyl(-3-isobutyl-1-)methylxanthine
-
 Homo sapiens
Cilostamide
-
 Homo sapiens
rolipram
-
 Homo sapiens
vinpocetine
-
 Homo sapiens
zaprinast
-
 Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ Ca2+/calmodulin stimulated Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q01064
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3',5'-cGMP + H2O
-
 Homo sapiens 5'-GMP
-
 ?
nucleoside 3',5'-cyclic phosphate + H2O
-
 Homo sapiens nucleoside 5'-phosphate
-
 ?