Any feedback?
Literature summary for 3.1.4.12 extracted from
- Substrate specificity of the neutral sphingomyelinase from Trypanosoma brucei (2018), Parasitology, 146, 604-616 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli BL21/pLysSGold cells | Trypanosoma brucei |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Trypanosoma brucei | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ceramide 1-phosphate + H2O | - |
Trypanosoma brucei | ? | - |
? |  |
| lyso-phosphatidylcholine + H2O | - |
Trypanosoma brucei | ? | - |
? | |
| additional information | the enzyme is inactive towards sphingosine 1-phosphate and phosphatidylcholine | Trypanosoma brucei | ? | - |
? | |
| sphingomyelin + H2O | the enzyme is active towards sphingomyelin species with a range of fatty acid chain lengths (C16-C24) | Trypanosoma brucei | ceramide + phosphocholine | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| neutral sphingomyelinase | - |
Trypanosoma brucei |
| nSMase | - |
Trypanosoma brucei |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
