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Literature summary for 3.1.4.12 extracted from

  • Tallima, H.; Al-Halbosiy, M.F.; El Ridi, R.
    Enzymatic activity and immunolocalization of Schistosoma mansoni and Schistosoma haematobium neutral sphingomyelinase (2011), Mol. Biochem. Parasitol., 178, 23-28.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
GW4869
-
Schistosoma haematobium
GW4869
-
Schistosoma mansoni

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ dependent on Schistosoma mansoni
Mg2+ dependent on Schistosoma haematobium

Organism

Organism UniProt Comment Textmining
Schistosoma haematobium
-
-
-
Schistosoma mansoni
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
gut
-
Schistosoma mansoni
-
gut
-
Schistosoma haematobium
-
integument
-
Schistosoma mansoni
-
integument
-
Schistosoma haematobium
-
additional information immunolocalization study of Mg2+-dependent neutral sphingomyelinase, overview Schistosoma mansoni
-
additional information immunolocalization study of Mg2+-dependent neutral sphingomyelinase, overview Schistosoma haematobium
-

Synonyms

Synonyms Comment Organism
neutral sphingomyelinase
-
Schistosoma mansoni
neutral sphingomyelinase
-
Schistosoma haematobium
nSMase
-
Schistosoma mansoni
nSMase
-
Schistosoma haematobium

General Information

General Information Comment Organism
additional information comparison of in vivo activity of nSMase in Schistosoma mansoni with the activity in Schistosoma haematobium, overview Schistosoma mansoni
additional information comparison of in vivo activity of nSMase in Schistosoma mansoni with the activity in Schistosoma haematobium, overview Schistosoma haematobium
physiological function the enzyme controls hydrolysis of surface membrane sphingomyelin molecules, thus allowing nutrients, but not host antibodies, to access proteins at the host-parasite interface Schistosoma mansoni
physiological function the enzyme controls hydrolysis of surface membrane sphingomyelin molecules, thus allowing nutrients, but not host antibodies, to access proteins at the host-parasite interface Schistosoma haematobium