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Literature summary for 3.1.4.12 extracted from

  • Marco, C.; Jimenez-Lopez, J.M.; Rios-Marco, P.; Segovia, J.L.; Carrasco, M.P.
    Hexadecylphosphocholine alters nonvesicular cholesterol traffic from the plasma membrane to the endoplasmic reticulum and inhibits the synthesis of sphingomyelin in HepG2 cells (2009), Int. J. Biochem. Cell Biol., 41, 1296-1303.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Bacillus cereus
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-
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
sphingomyelin + H2O
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Bacillus cereus N-acylsphingosine + choline phosphate
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?

Synonyms

Synonyms Comment Organism
SMase
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Bacillus cereus
sphingomyelinase
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Bacillus cereus

General Information

General Information Comment Organism
physiological function in HepG2 cells SMase treatment significantly enhances the esterification of cholesterol by a 50% with respect to control cells Bacillus cereus