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Literature summary for 3.1.4.12 extracted from

  • Jafurulla, M.; Pucadyil, T.J.; Chattopadhyay, A.
    Effect of sphingomyelinase treatment on ligand binding activity of human serotonin1A receptors (2008), Biochim. Biophys. Acta, 1778, 2022-2025.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the specific ligand binding activity of the serotonin1A receptor in membranes isolated from CHO-5-HT1AR cells is increased upon sphingomyelinase treatment (25 or 50 mU/ml) for 90 min in DMEM/F-12 medium under serum free condition ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the specific ligand binding activity of the serotonin1A receptor in membranes isolated from CHO-5-HT1AR cells is increased upon sphingomyelinase treatment (25 or 50 mU/ml) for 90 min in DMEM/F-12 medium under serum free condition Homo sapiens ?
-
?
sphingomyelin + H2O
-
Homo sapiens N-acylsphingosine + choline phosphate
-
?

Synonyms

Synonyms Comment Organism
SMase
-
Homo sapiens
sphingomyelinase
-
Homo sapiens