Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphatidylcholine induces neutral sphingomyelinase activity | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
desipramine | inhibits the acid SMase, and lipopolysaccharide induction of interleukin-8 synthesis in vivo | Homo sapiens | |
GW4869 | inhibits the neutral SMase, and lipopolysaccharide induction of interleukin-8 synthesis in vivo | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | a role for neutral sphingomyelinase activation in the inhibition of LPS action by phospholipid oxidation, regulation, overview | ? | - |
? | |
sphingomyelin + H2O | Homo sapiens | - |
N-acylsphingosine + choline phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epithelial cell | airway | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | a role for neutral sphingomyelinase activation in the inhibition of LPS action by phospholipid oxidation, regulation, overview | Homo sapiens | ? | - |
? | |
sphingomyelin + H2O | - |
Homo sapiens | N-acylsphingosine + choline phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
acid sphingomyelinase | - |
Homo sapiens |
neutral sphingomyelinase | - |
Homo sapiens |