Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | activation of acid sphingomyelinase by gemcitabine or doxorubicin, respectively, via reactive oxygen species | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
transfection of murine and human glioma cell lines Gl-261 and U-373 with acid sphingomyelinase results in a marked sensitization of glioma cells to gemcitabine and doxorubicin, respectively | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
acid sphingomyelinase | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5 | - |
assay at | Homo sapiens |