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Literature summary for 3.1.4.12 extracted from

  • Stoffel, W.; Jenke, B.; Block, B.; Zumbansen, M.; Koebke, J.
    Neutral sphingomyelinase 2 (smpd3) in the control of postnatal growth and development (2005), Proc. Natl. Acad. Sci. USA, 102, 4554-4559.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus SMPD3 plays a pivotal role in the control of late embryonic and postnatal development: the smpd3-null mouse develops a novel form of dwarfism and delayed puberty as part of a hypothalamus-induced combined pituitary hormone deficiency ?
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?

Organism

Organism UniProt Comment Textmining
Mus musculus Q9JJY3
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information SMPD3 plays a pivotal role in the control of late embryonic and postnatal development: the smpd3-null mouse develops a novel form of dwarfism and delayed puberty as part of a hypothalamus-induced combined pituitary hormone deficiency Mus musculus ?
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?
sphingomyelin + H2O
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Mus musculus N-acylsphingosine + choline phosphate
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?

Synonyms

Synonyms Comment Organism
neutral sphingomyelinase 2
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Mus musculus
Smpd3
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Mus musculus