Application | Comment | Organism |
---|---|---|
medicine | inhibiting or stopping N-SMase activity is an important strategy to prevent neuron death from ischemia | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
[(2S)-1,1-difluoro-3-(hexadecanoylamino)-2,4-dihydroxy-4-phenylbutyl]phosphonic acid SMA-3 | - |
Rattus norvegicus | |
[(4S)-1,1-difluoro-3-(hexadecanoylamino)-4-hydroxy-4-phenylbutyl]phosphonic acid | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
plasma membrane | - |
Rattus norvegicus | 5886 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | neutral sphingomyelinase is a key component of the signaling pathway in cytokine- and other stress-induced cellular responses | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
PC-12 cell | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | neutral sphingomyelinase is a key component of the signaling pathway in cytokine- and other stress-induced cellular responses | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
N-SMase | - |
Rattus norvegicus |
neutral sphingomyelinase | - |
Rattus norvegicus |