Protein Variants | Comment | Organism |
---|---|---|
H148G | mutant enzyme shows no sphingomyelinase activity | Clostridium perfringens |
Y57A | mutant enzyme shows 111.3% of wild-type sphingomyelinase activity | Clostridium perfringens |
Y57C/C169L | mutant enzyme shows 104.1% of wild-type sphingomyelinase activity | Clostridium perfringens |
Y57F | mutant enzyme shows 105.2% of wild-type sphingomyelinase activity | Clostridium perfringens |
Y57L | mutant enzyme shows 103.1% of wild-type sphingomyelinase activity | Clostridium perfringens |
Y65A | mutant enzyme shows 89.4% of wild-type sphingomyelinase activity | Clostridium perfringens |
Y65C/C169L | mutant enzyme shows 98.1% of wild-type sphingomyelinase activity | Clostridium perfringens |
Y65F | mutant enzyme shows 95.6% of wild-type sphingomyelinase activity | Clostridium perfringens |
Y65L | mutant enzyme shows 99.2% of wild-type sphingomyelinase activity | Clostridium perfringens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Clostridium perfringens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
wild-type and mutant enzymes | Clostridium perfringens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
sphingomyelin + H2O | - |
Clostridium perfringens | N-acylsphingosine + choline phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
alpha-toxin | - |
Clostridium perfringens |