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Literature summary for 3.1.4.12 extracted from

  • Won, J.S.; Im, Y.B.; Khan, M.; Singh, A.K.; Singh, I.
    The role of neutral sphingomyelinase produced ceramide in lipopolysaccharide-mediated expression of inducible nitric oxide synthase (2004), J. Neurochem., 88, 583-593.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
3-O-methylsphingomyelin
-
Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
sphingomyelin + H2O Rattus norvegicus ceramide production by neutral sphingomyelinase is a key mediator in the induction of inducible nitric oxide synthase N-acylsphingosine + choline phosphate
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
glioma cell C6-glioma cells Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
sphingomyelin + H2O
-
Rattus norvegicus N-acylsphingosine + choline phosphate
-
?
sphingomyelin + H2O ceramide production by neutral sphingomyelinase is a key mediator in the induction of inducible nitric oxide synthase Rattus norvegicus N-acylsphingosine + choline phosphate
-
?

Synonyms

Synonyms Comment Organism
neutral sphingomyelinase
-
Rattus norvegicus
nSMase
-
Rattus norvegicus