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Literature summary for 3.1.4.12 extracted from

  • Gosh, N.; Sabbadini, R.; Chatterjee, S.
    Identification, partial purification, and localization of a neutral sphingomyelinase in rabbit skeletal muscle: neutral sphingomyelinase in skeletal muscle (1998), Mol. Cell. Biochem., 189, 161-168.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Cu2+
-
Oryctolagus cuniculus

Localization

Localization Comment Organism GeneOntology No. Textmining
T-tubule majority in junctional transverse tubules Oryctolagus cuniculus 30315
-

Metals/Ions

Metals/Ions Comment Organism Structure
Li+
-
Oryctolagus cuniculus
Mg2+ activates the 92000 Da isoform but not the 53000 Da one Oryctolagus cuniculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
53000
-
1 * 92000 + 1 * 53000, Western blotting analysis and activity gel analysis Oryctolagus cuniculus
92000
-
1 * 92000 + 1 * 53000, Western blotting analysis and activity gel analysis Oryctolagus cuniculus

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
skeletal muscle
-
Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
sphingomyelin + H2O
-
Oryctolagus cuniculus N-acylsphingosine + choline phosphate
-
?

Subunits

Subunits Comment Organism
dimer 1 * 92000 + 1 * 53000, Western blotting analysis and activity gel analysis Oryctolagus cuniculus