Activating Compound | Comment | Organism | Structure |
---|---|---|---|
cholate | - |
Rattus norvegicus | |
Cutsum | - |
Rattus norvegicus | |
Detergents | activation | Rattus norvegicus | |
ethanol | - |
Rattus norvegicus | |
taurocholate | - |
Rattus norvegicus | |
Triton X-100 | - |
Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ceramide | - |
Rattus norvegicus | |
cetyltrimethylammonium bromide | - |
Rattus norvegicus | |
fatty acids | - |
Rattus norvegicus | |
lecithin | - |
Rattus norvegicus | |
phosphatidylinositol | - |
Rattus norvegicus | |
phosphatidylserine | - |
Rattus norvegicus | |
sphingosine | - |
Rattus norvegicus | |
taurocholate | in presence of Triton X-100 | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.13 | - |
sphingomyelin | - |
Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
sphingomyelin + H2O | Rattus norvegicus | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
18fold | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
Storage Stability | Organism |
---|---|
-20°C, 250 mM sucrose, 20 mM Tris buffer, several weeks | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
sphingomyelin + H2O | D-erythrosphingosine or dihydroxysphingosine configuration of sphingomyelin results in a 3-5fold faster hydrolysis in comparison to a D-threo or L-erythro configuration | Rattus norvegicus | N-acylsphingosine + choline phosphate | - |
ir | |
sphingomyelin + H2O | - |
Rattus norvegicus | ? | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5 | - |
- |
Rattus norvegicus |