Application | Comment | Organism |
---|---|---|
drug development | PLCgamma1 inhibitors may have potential therapeutic applications for the clinical treatment of tumor metastasis | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | experimental metastasis assays with tetracycline in nude mice show that inducible knockdown of PLCgamma1 strongly inhibits development of MDA-MB-231-derived lung metastasis and reverts metastasis formation | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
breast cancer patients | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HEK-293T cell | - |
Homo sapiens | - |
lymph node | metastases | Homo sapiens | - |
MDA-MB-231 cell | pSuperior 3Mut and pSuperior shPLCgamma1 | Homo sapiens | - |
MDA-MB-435 cell | - |
Homo sapiens | - |
TSA cell | - |
Homo sapiens | - |
U-87MG cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
phospholipase Cgamma1 | - |
Homo sapiens |
PLCgamma1 | - |
Homo sapiens |