Cloned (Comment) | Organism |
---|---|
expression in baculovirus-infected insect cells | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | wild-type Rac GTPase with guanosine 5'-(3-O-thio)triphosphate causes a marked stimulation of PLCgamma2 but has no effect on the activity of PLCgamma1. The mechanism of PLCgamma2 activation by Rac GTPase involves neither protein phosphorylation nor PI3K-mediated generation of phosphatidylinositol 3,4,5-trisphosphate | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O | - |
Homo sapiens | 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol | - |
? | |
additional information | wild-type Rac GTPase with guanosine 5'-(3-O-thio)triphosphate causes a marked stimulation of PLCgamma2 but has no effect on the activity of PLCgamma1. The mechanism of PLCgamma2 activation by Rac GTPase involves neither protein phosphorylation nor PI3K-mediated generation of phosphatidylinositol 3,4,5-trisphosphate | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
phospholipase C-gamma2 | - |
Homo sapiens |