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Literature summary for 3.1.4.11 extracted from

  • Nakahara, M.; Shimozawa, M.; Nakamura, Y.; Irino, Y.; Morita, M.; Kudo, Y.; Fukami, K.
    A novel phospholipase C, PLC(eta)2, is a neuron-specific isozyme (2005), J. Biol. Chem., 280, 29128-29134.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane
-
Mus musculus 5886
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ maximal activity at 0.001 mM Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus the neuron-specific enzyme may be important for the formation and/or maintenance of the neuronal network in the postnatal brain ?
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus A2AP18
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain PLCeta2 is restricted to brain. PLCeta2 gradually increases during brain development. PLCeta2 is not detected in embryos. At 1 week after birth PLCeta2 is barely detected and expression is first observed at weeks after birth Mus musculus
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cerebral cortex PLCeta2 is restricted to brain. PLCeta2 gradually increases during brain development. PLCeta2 is not detected in embryos. At 1 week after birth PLCeta2 is barely detected and expression is first observed at weeks after birth Mus musculus
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hippocampus PLCeta2 is restricted to brain. PLCeta2 gradually increases during brain development. PLCeta2 is not detected in embryos. At 1 week after birth PLCeta2 is barely detected and expression is first observed at weeks after birth Mus musculus
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olfactory bulb PLCeta2 is restricted to brain. PLCeta2 gradually increases during brain development. PLCeta2 is not detected in embryos. At 1 week after birth PLCeta2 is barely detected and expression is first observed at weeks after birth Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
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Mus musculus 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
?
additional information the neuron-specific enzyme may be important for the formation and/or maintenance of the neuronal network in the postnatal brain Mus musculus ?
-
?

Synonyms

Synonyms Comment Organism
PLCeta2
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Mus musculus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
-
Mus musculus