Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | cleavage of GPI-anchored proteins by PI-PLC is influenced by bilayer fluidity, higher fluidity activates | Bacillus thuringiensis |
Crystallization (Comment) | Organism |
---|---|
- |
Listeria monocytogenes |
free form, in complex with myo-inositol and with glucosaminyl(alpha1-6)-D-myo-inositol | Bacillus cereus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kinetic study of 5-nucleotidase cleavage | Bacillus thuringiensis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus cereus | - |
- |
- |
Bacillus thuringiensis | - |
- |
- |
Clostridium novyi | - |
- |
- |
Listeria monocytogenes | - |
- |
- |
Staphylococcus aureus | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol | mechanism | Bacillus cereus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glycosylphosphatidylinositol + H2O | catalytic mechanism | Bacillus cereus | ? | - |
? | |
additional information | PI-PLC has a high affinity for the glycosylphosphatidylinositol anchor of GPI-anchored proteins, e.g. 5-nucleotidase and alkaline phosphatase, and catalyzes cleavage in vitro to release a soluble protein and diacylglycerol, which remains in the membrane | Staphylococcus aureus | ? | - |
? | |
additional information | PI-PLC has a high affinity for the glycosylphosphatidylinositol anchor of GPI-anchored proteins, e.g. 5-nucleotidase and alkaline phosphatase, and catalyzes cleavage in vitro to release a soluble protein and diacylglycerol, which remains in the membrane | Bacillus thuringiensis | ? | - |
? | |
additional information | PI-PLC has a high affinity for the glycosylphosphatidylinositol anchor of GPI-anchored proteins, e.g. 5-nucleotidase and alkaline phosphatase, and catalyzes cleavage in vitro to release a soluble protein and diacylglycerol, which remains in the membrane | Clostridium novyi | ? | - |
? | |
additional information | PI-PLC has a high affinity for the glycosylphosphatidylinositol anchor of GPI-anchored proteins, e.g. 5-nucleotidase and alkaline phosphatase, and catalyzes cleavage in vitro to release a soluble protein and diacylglycerol, which remains in the membrane, enzyme structure | Bacillus cereus | ? | - |
? | |
phosphatidylinositol + H2O | phosphatidylinositol-specific, catalytic mechanism | Bacillus cereus | diacylglycerol + myo-inositol 1-phosphate | - |
? |