Any feedback?
Literature summary for 3.1.4.11 extracted from
- Characterization and properties of a phosphatidylinositol phosphodiesterase (phospholipase C) from platelet cytosol (1979), FEBS Lett., 100, 367-370.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | at high concentrations | Homo sapiens |  |
| EDTA | 2 mM, 70% inhibition | Homo sapiens | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Homo sapiens | 5829 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | optimal concentrations are 0.3 mM and 8 mM using 0.2 mM and 0.4 mM phosphatidylinositol | Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| blood platelet | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| arachidonoyl-phosphatidylinositol + H2O | - |
Homo sapiens | 1,2-diarachidonoyl-sn-glycerol + 1D-myo-inositol 1-phosphate | - |
? | |
| phosphatidylinositol + H2O | - |
Homo sapiens | 1D-myo-inositol-1-phosphate + diacylglycerol | in vitro 1D-myo-inositol-1,2-cyclic phosphate is also formed | ? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| phosphatidylinositol phosphodiesterase | - |
Homo sapiens |
| phospholipase C | - |
Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6 | - |
- |
Homo sapiens |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 6 | 7 | - |
Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
