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Literature summary for 3.1.31.1 extracted from

  • Li, C.L.; Yang, W.Z.; Shi, Z.; Yuan, H.S.
    Tudor staphylococcal nuclease is a structure-specific ribonuclease that degrades RNA at unstructured regions during microRNA decay (2018), RNA, 24, 739-748 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.31.1

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ dependent on Caenorhabditis elegans

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
136000
-
 analytical ultracentrifugation Caenorhabditis elegans

Organism

Organism UniProt Comment Textmining
Caenorhabditis elegans Q19328
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
RNA + H2O the enzyme cleaves RNA chains at the 5'-side of the phosphodiester linkage to produce degraded fragments with 5'-hydroxyl and 3'-phosphate ends. cTSN degrades single-stranded RNA and double-stranded RNA containing mismatched base pairs, but is not restricted to those containing multiple I/U and U/I pairs. Tudor staphylococcal nuclease is a structure-specific ribonuclease targeting single-stranded RNA and unstructured regions of double-stranded RNA Caenorhabditis elegans ?
-
 ?

Subunits

Subunits Comment Organism
monomer
-
 Caenorhabditis elegans

Synonyms

Synonyms Comment Organism
cTSN
-
 Caenorhabditis elegans
TSN
-
 Caenorhabditis elegans
tudor staphylococcal nuclease
-
 Caenorhabditis elegans

General Information

General Information Comment Organism
physiological function the enzyme cooperates with RNA editing to eliminate duplex RNA in cell defense. Tudor staphylococcal nuclease selects and degrades RNA during microRNA decay Caenorhabditis elegans