Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q7KZF4 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
U-87MG cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
Tudor-staphylococcal nuclease | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | the downregulated expression of Tudor-staphylococcal nuclease can decrease cancer malignancy, and the overexpression can increase viability and migration potential of various tumor cell types. Tudor-SN silencing suppresses the expression of alkylglycerone phosphate synthase (AGPS) and the activity of the mechanistic target of rapamycin (mTOR) signaling pathway. NF-kappaB and miR-127 may be the mediators of Tudor-SN-regulated alkylglycerone phosphate synthase (AGPS) via the mTOR signaling pathway | Homo sapiens |