Literature summary for 3.1.31.1 extracted from

Patel, S.; Sasidhar, Y.U.
A shorter peptide model from staphylococcal nuclease for the folding-unfolding equilibrium of a beta-hairpin shows that unfolded state has significant contribution from compact conformational states (2008), J. Struct. Biol., 164, 60-74.

Application

Application	Comment	Organism
analysis	peptide model LMYKGQPM from staphylococcal nuclease can serve as model for faster folding beta-hairpins pursuing fast folding events	Staphylococcus sp.

Crystallization (Commentary)

Crystallization (Comment)	Organism
LMYKGQPM, short peptide model from staphylococcal nuclease to model the conformational equilibrium between a hairpin conformation and its unfolded state (molecular dynamics simulation), in water, cubic model system, total simulation time 600 ns, starting from a polyproline II conformation, GROMOS96 force field under NVT conditions, 27°C: native and non-native hairpins are very close in free energies, interconversion can happen only through the unfolded conformation. Both folding and unfolding events display single exponential kinetics	Staphylococcus sp.

Crystallization (Comment)

Organism

LMYKGQPM, short peptide model from staphylococcal nuclease to model the conformational equilibrium between a hairpin conformation and its unfolded state (molecular dynamics simulation), in water, cubic model system, total simulation time 600 ns, starting from a polyproline II conformation, GROMOS96 force field under NVT conditions, 27°C: native and non-native hairpins are very close in free energies, interconversion can happen only through the unfolded conformation. Both folding and unfolding events display single exponential kinetics

Staphylococcus sp.

General Stability

General Stability	Organism
native hairpin conformation is more stable than non-native conformation	Staphylococcus sp.

Organism

Organism	UniProt	Comment	Textmining
Staphylococcus sp.	-	-	-

Synonyms

Synonyms	Comment	Organism
staphylococcal nuclease	-	Staphylococcus sp.

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Release 2023.1 (January 2023)