Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | molecular dynamic simulations, interaction with enzyme monomer-DNA complex via 6 ligands, which are changing during the reaction simulation, e.g. Asn119 loses its coordination while Glu127 becomes a ligand, overview | Serratia marcescens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Serratia marcescens | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
endonucleolytic cleavage to 5'-phosphomononucleotide and 5'-phosphooligonucleotide end-products | catalytic mechanism, enzyme monomer-DNA binding complex, hydration sites and influence of solvent on structure and reaction, active site structure | Serratia marcescens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the subunits of the dimer function independently as monomers, molecular dynamic simulations involving Mg2+, modelling of complex building with DNA | Serratia marcescens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | monomer and dimer of the enzyme are catalytically active | Serratia marcescens |
monomer | monomer and dimer of the enzyme are catalytically active | Serratia marcescens |
More | the subunits of the dimer function independently as monomers, molecular dynamic simulations, modelling of complex building with DNA, hydration sites of the enzyme depending on solvent density, overview | Serratia marcescens |
Synonyms | Comment | Organism |
---|---|---|
Serratia marcescens endonuclease | - |
Serratia marcescens |
SMnase | - |
Serratia marcescens |