Cloned (Comment) | Organism |
---|---|
enzyme isoform of brain: G6PC3 | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.3 | - |
D-glucose 6-phosphate | pH 6.5, in disrupted vesicles | Rattus norvegicus | |
0.5 | - |
D-glucose 6-phosphate | pH 5.5, in disrupted vesicles | Rattus norvegicus | |
1 | - |
D-glucose 6-phosphate | pH 5.5, in disrupted vesicles | Homo sapiens | |
1.3 | - |
D-glucose 6-phosphate | pH 6.5, in not disrupted vesicles | Rattus norvegicus | |
2 | - |
D-glucose 6-phosphate | pH 6.5, in disrupted vesicles | Homo sapiens | |
4.1 | - |
D-glucose 6-phosphate | pH 5.5, in not disrupted vesicles | Homo sapiens | |
4.3 | - |
D-glucose 6-phosphate | pH 6.5, in not disrupted vesicles | Homo sapiens | |
5.1 | - |
D-glucose 6-phosphate | pH 5.5, in not disrupted vesicles | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
microsome | - |
Rattus norvegicus | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
38730 | - |
calculation from sequence of cDNA | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9BUM1 | - |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | expression of G6PC3 isoform | Homo sapiens | - |
heart | expression of G6PC3 isoform | Homo sapiens | - |
kidney | expression of G6PC1 and G6PC3 isoforms | Homo sapiens | - |
liver | - |
Rattus norvegicus | - |
liver | expression of G6PC1 isoform | Homo sapiens | - |
placenta | expression of G6PC3 isoform | Homo sapiens | - |
skeletal muscle | expression of G6PC3 isoform | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-Deoxy-D-glucose 6-phosphate + H2O | a better substrate in disrupted vesicles at pH 5.5 and pH 6.5 | Homo sapiens | 2-Deoxy-D-glucose + phosphate | - |
? | |
2-Deoxy-D-glucose 6-phosphate + H2O | only in disrupted vesicles | Rattus norvegicus | 2-Deoxy-D-glucose + phosphate | - |
? | |
D-glucose 6-phosphate + H2O | - |
Homo sapiens | D-glucose + phosphate | - |
? | |
D-glucose 6-phosphate + H2O | best substrate in disrupted and not disrupted vesicles at pH 5.5 and pH 6.5 | Rattus norvegicus | D-glucose + phosphate | - |
? | |
p-nitrophenyl phosphate + H2O | - |
Rattus norvegicus | p-nitrophenol + phosphate | - |
? | |
p-nitrophenyl phosphate + H2O | best substrate in disrupted and not disrupted vesicles at pH 5.5 and pH 6.5 | Homo sapiens | p-nitrophenol + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | structure comparison of G6PC1 and G6PC3 isoforms | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6 | - |
in disruptes vesicles | Homo sapiens |
6.5 | - |
in disruptes vesicles | Rattus norvegicus |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Homo sapiens | - |
- |
8.5 |